Jebel Moya (Sudan): new dates from a mortuary complex at the southern Meroitic frontier

This paper proposes a new chronology for the burial complex at Jebel Moya, south-central Sudan. It reassesses the body of evidence from Sir Henry Wellcome's original 1911–1914 excavations in order to place the site within a firm chronological framework by: (a) applying an attribute-based approach to discern discrete pottery assemblages; and (b) applying initial OSL dates to facilitate the reliable dating of this site for the first time. Jebel Moya is re-interpreted as a burial complex situated on the southern periphery of the late Meroitic state, and its potential to serve as a chronological and cultural reference point for future studies in south-central and southern Sudan is outlined

Optimal receptor-cluster size determined by intrinsic and extrinsic noise

Biological cells sense external chemical stimuli in their environment using cell-surface receptors. To increase the sensitivity of sensing, receptors often cluster, most noticeably in bacterial chemotaxis, a paradigm for signaling and sensing in general. While amplification of weak stimuli is useful in absence of noise, its usefulness is less clear in presence of extrinsic input noise and intrinsic signaling noise. Here, exemplified on bacterial chemotaxis, we combine the allosteric Monod-Wyman- Changeux model for signal amplification by receptor complexes with calculations of noise to study their interconnectedness. Importantly, we calculate the signal-to-noise ratio, describing the balance of beneficial and detrimental effects of clustering for the cell. Interestingly, we find that there is no advantage for the cell to build receptor complexes for noisy input stimuli in absence of intrinsic signaling noise. However, with intrinsic noise, an optimal complex size arises in line with estimates of the sizes of chemoreceptor complexes in bacteria and protein aggregates in lipid rafts of eukaryotic cells.Comment: 15 pages, 12 figures,accepted for publication on Physical Review

IoT and Its Implications for Informed Consent

This report is based on a three-hour long workshop between representatives of the PETRAS IoT Hub, Pinsent Masons, and the HMG Department for Transport. The workshop is part of an ongoing investigation that explores the connections between some of the different dimensions likely to shape conceptions and applications of consent in the emerging Internet of Things (IoT). The impetus for the workshop was the recognition that two significant developments will challenge conventional approaches to online consent. From a technical perspective, the IoT will significantly increase personal data collection, use and re-use. From a regulatory perspective, the General Data Protection Regulation (GDPR) which comes into force in May 2018, will make much higher demands on practices of giving and obtaining consent. Combined, these two factors suggest that consent will be a major issue for all actors in the next five years and it requires some careful analysis now in order to adequately prepare for these developments

Voice Flows To And Around Leaders: Understanding When Units Are Helped Or Hurt By Employee Voice

In two studies, we develop and test theory about the relationship between speaking up, one type of organizational citizenship behavior, and unit performance by accounting for where employee voice is flowing. Results from a qualitative study of managers and professionals across a variety of industries suggest that voice to targets at different formal power levels (peers or superiors) and locations in the organization (inside or outside a focal unit) differs systematically in terms of its usefulness in generating actions to a unit's benefit on the issues raised and in the likely information value of the ideas expressed. We then theorize how distinct voice flows should be differentially related to unit performance based on these core characteristics and test our hypotheses using time-lagged field data from 801 employees and their managers in 93 units across nine North American credit unions. Results demonstrate that voice flows are positively related to a unit's effectiveness when they are targeted at the focal leader of that unitwho should be able to take actionwhether from that leader's own subordinates or those in other units, and negatively related to a unit's effectiveness when they are targeted at coworkers who have little power to effect change. Together, these studies provide a structural framework for studying the nature and impact of multiple voice flows, some along formal reporting lines and others that reflect the informal communication structure within organizations. This research demonstrates that understanding the potential performance benefits and costs of voice for leaders and their units requires attention to the structure and complexity of multiple voice flows rather than to an undifferentiated amount of voice.Business Administratio

Simultaneous Graph Embeddings with Fixed Edges

We study the problem of simultaneously embedding several graphs on the same vertex set in such a way that edges common to two or more graphs are represented by the same curve. This problem is known as simultaneously embedding graphs with fixed edges. We show that this problem is closely related to the weak realizability problem: Can a graph be drawn such that all edge crossings occur in a given set of edge pairs? By exploiting this relationship we can explain why the simultaneous embedding problem is challenging, both from a computational and a combinatorial point of view. More precisely, we prove that simultaneously embedding graphs with fixed edges is NP-complete even for three planar graphs. For two planar graphs the complexity status is still open

Sequence Dependence of Self-Interacting Random Chains

We study the thermodynamic behavior of the random chain model proposed by Iori, Marinari and Parisi, and how this depends on the actual sequence of interactions along the chain. The properties of randomly chosen sequences are compared to those of designed ones, obtained through a simulated annealing procedure in sequence space. We show that the transition to the folded phase takes place at a smaller strength of the quenched disorder for designed sequences. As a result, folding can be relatively fast for these sequences.Comment: 14 pages, uuencoded compressed postscript fil